Dr. Peter Costantino has developed a product for replacing and regenerating bone.This material is called Hydroxyapatite cement, which can be likened to a plaster of paris compound, is used as a foundation for bone regeneration, facilitating previously impossible cranio-facial repairs and reconstruction. BoneSource® Classic is an osteoconductive, isothermic bone substitute (cement) made from calcium phosphate salts and sodium phosphate solution. BoneSource® Classic offers excellent biocompatibility and high mechanical stability while being easy to handle in the operating room.

Unique Features and Benefits:

• An ideal bone graft substitute for non-stress-bearing applications in skeletal tissues, such as filling cranial defects.

• Quick - saves valuable time in the OR by providing powder pre-packaged in a conventient mixing bowl.

• Easy - eliminates potential variability and simplifies mixing by providing a set amount of sodium phosphate solution that is completely injected into the powder.

• Proven - clinically proven with more than ten years of supportive literature

• Self-setting cement

• Forms putty-like substance when mixed with sodium phosphate solution that can be easily shaped and applied.

• Forms a structurally stable implant after 5-10 minutes.

• Converts to hydroxyapatite within 4-6 hours.

• Excellent biocompatibility

• Maintains shape and volume over time

• Remodels to bone over time

• Isothermic - no damaging heat release to surrounding tissue

• Available in five sizes: 2.5g (1.5cc); 5g (3cc); 10g (6cc); 25g (15cc); 50g (30cc)
  

Tissue Reengineering is Revolutionizing Surgical Outcomes

Dr. Peter Costantino has developed a product for tissue reengineering called AlloDerm®. Tissue engineering is a hot topic for researchers, and close attention to AlloDerm® is being paid by researchers who are attempting to generate human organs. Dr. Costantino states that, "many doctors and HMOs are unaware of our reconstructive capability. Instead, they steer their tumor-stricken patients to radiation and chemo, which could be less effective than surgery."

AlloDerm® is real human tissue that is decellularized to remove the risk of rejection or inflammation. It is then freeze-dried through a patented process that maintains the crucial elements of the tissue structure (collagen, elastin, proteoglycans) and packaged with a shelf life up to two years. AlloDerm® is available in various sizes to increase keratinized gingiva, for soft tissue flap extensions over bone grafts, and for recession defects